A major annual cancer report has revealed a mix of good news and points of concern.

Cancer diagnoses are expected to exceed two million in 2025, with approximately 618,120 deaths predicted, according to the American Cancer Society’s annual cancer trends report, which was published today in CA: A Cancer Journal for Clinicians.

ACS researchers compiled data from central cancer registries and from the National Center for Health Statistics.

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While mortality rates have declined, certain groups are seeing a spike in diagnoses, the report noted.

“Continued reductions in cancer mortality because of drops in smoking, better treatment and earlier detection is certainly great news,” said lead author Rebecca Siegel, senior scientific director of surveillance research at the ACS in Georgia, in a press release.

“However, this progress is tempered by rising incidences in young and middle-aged women, who are often the family caregivers, and a shifting cancer burden from men to women, harkening back to the early 1900s, when cancer was more common in women.”

Overall decline in death rates

Cancer death rates dropped 34% between 1991 and 2022, according to the ACS report.

That equates to approximately 4.5 million deaths avoided due to early detection, reductions in smoking, and improvements in treatment, the report stated.

Several factors likely contributed to this decline, noted John D. Carpten, Ph.D., chief scientific officer at City of Hope, a national cancer research and treatment organization in California.

“I think a big one is smoking cessation and the battle against lung cancer, which has always been the most common form of cancer and is tied to tobacco use,” Carpten told Fox News Digital in an on-camera interview.

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“But without a doubt, I think new and better methods for early detection, and screening for colorectal cancer and other forms of the disease, have also allowed us to see a decrease.” 

Lifestyle improvements have also helped to decrease mortality, he said, along with the development of new and better therapies for cancer.

“Screening programs are a critical component of early detection, and expanding access to these services will save countless lives.” (iStock)

Despite overall declines in mortality, the report revealed that death rates are rising for cancers of the oral cavity, pancreas, uterine corpus and liver (for females).

Some common cancers have also seen an increase in diagnoses, including breast (female), prostate, pancreatic, uterine corpus, melanoma (female), liver (female) and oral cancers associated with the human papillomavirus, the report stated.

Increased diagnoses among certain groups

Diagnoses for many cancer types are increasing among certain groups.

Cancer rates for women 50 to 64 years of age have surpassed those for men, the report revealed. For women under 50, rates are 82% higher than males in that age group.

The report revealed that diagnoses of colorectal cancer in men and women under 65 and cervical cancer in women between 30 and 44 years of age has increased. (iStock)

As far as what is influencing the “disconcerting trend” in women’s cancers, Carpten said it is likely “highly nuanced” and will require additional research.

“The decrease in fertility and increases in obesity that we’ve seen are risk factors for breast cancer, especially in postmenopausal middle-aged women,” he said. 

“But there could be other modifiable risk factors at play, like alcohol and physical activity.”

Cancer rates for women 50 to 64 years of age have surpassed those for men.

Another trend in the increase in early cancers is occurring in individuals under the age of 50, Carpten noted.

In particular, the report revealed that diagnoses of colorectal cancer in men and women under 65 and cervical cancer in women between 30 and 44 years of age has increased.

Some common cancers have also seen an increase in diagnoses, including breast (female), prostate, pancreatic, uterine corpus, melanoma (female), liver (female) and oral cancers associated with the human papillomavirus. (iStock)

The report also discusses inequities in cancer rates among certain ethnic groups, with Native American and Black people experiencing higher diagnoses of some cancer types.

“Progress against cancer continues to be hampered by striking, wide static disparities for many racial and ethnic groups,” said senior author Dr. Ahmedin Jemal, senior vice president of surveillance and health equity science at the ACS, in the release.

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The report shows mixed trends for children, with diagnoses declining in recent years for patients 14 years of age and younger, but rising for adolescents between 15 and 19.

“Mortality rates have dropped by 70% in children and by 63% in adolescents since 1970, largely because of improved treatment for leukemia,” the ACS stated in the release.

Pancreatic cancer a growing concern

The ACS report also warns about “lagging progress” against pancreatic cancer, the third-leading cause of cancer death in the U.S. 

The ACS report also warns about “lagging progress” against pancreatic cancer, the third-leading cause of cancer death in the U.S.  (iStock)

Rates of diagnoses and deaths from the disease type are on the rise.

“Pancreatic is an incredibly deadly form of cancer,” Carpten said. 

One of the main issues with pancreatic cancer, he said, is that it sometimes can grow in an individual for up to 10 years before it’s detected.

“If we can identify those cancers when they’re at at a curable stage, we can improve outcomes.”

One of the best opportunities for beating pancreatic cancer is early detection, Carpten said. 

“By the time those cancers have advanced, they’ve spread to the liver or other organs, and they’re almost impossible to cure at that stage,” he said.

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“If we can identify those cancers when they’re at a curable stage, we can improve outcomes.”

‘It takes a village’

Making progress in fighting cancer “takes a village,” Carpten told Fox News Digital.

“It will require partnerships between the community, the health care system, cancer researchers, government, industry — we all have to work together if we want to continue to see a decrease and an ultimate increase in cures,” he said.

“We all have to work together if we want to continue to see a decrease and an ultimate increase in cures,” a cancer researcher said. (iStock)

Dr. Wayne A. I. Frederick, interim chief executive officer of the American Cancer Society and the American Cancer Society Cancer Action Network (ACS CAN), stated that the report highlights the need to “increase investment in both cancer treatment and care, including equitable screening programs.”

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“Screening programs are a critical component of early detection, and expanding access to these services will save countless lives,” he said in the release.

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“We also must address these shifts in cancer incidence, mainly among women. A concerted effort between health care providers, policymakers and communities needs to be prioritized to assess where and why mortality rates are rising.”

Fox News Digital reached out to the ACS for further comment.

The U.S. Food and Drug Administration (FDA) has officially announced a ban on red dye No. 3, or erythrosine, from foods and oral medications due to a potential cancer risk.

Food manufacturers have until January 2027 to remove the dye (Red 3) from their products, and drug manufacturers have until January 2028, as reported by the Associated Press.

The dye was removed from cosmetics nearly 35 years ago for the same cancer-related concerns.

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Following the Wednesday announcement of the new ban, nutritionists and other health experts applauded the removal of the additives from America’s food supply.

Los Angeles-based registered dietitian nutritionist Ilana Muhlstein shared her excitement about the FDA “finally” banning the synthetic dye that has been in candy, cereals and strawberry-flavored drinks for “far too long.”

“What is wild is that this decision comes over three decades after the same dye was banned in cosmetics like lipstick because there was enough evidence linking it to cancer in animals,” she told Fox News Digital.

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“For years, consumer advocacy groups and researchers have pushed for this change, citing not only cancer risks but also potential links to hyperactivity and ADHD in kids.”

A certified holistic nutritionist (not pictured) warned that red dye No. 3 appears in some products that “you’d never expect.” (iStock)

Certified holistic nutritionist and The Power of Food Education founder Robin DeCicco, based in New York, commented that “it’s about time” Red 3 was banned.

“It never made sense to me why the dye was taken out of lipsticks and blushes 30 years ago but has been allowed to be in our food supply,” she reiterated to Fox News Digital. “There has been evidence of the dye causing cancer in rats for decades.”

“Our kids deserved better, and it’s frustrating that it took this long for action to be taken.”

Muhlstein expressed that while the ban is an “obvious win for public health,” she still feels “frustrated” that it took so long.

“The FDA became aware of the risks in the 1980s, and other countries, like those in the EU, banned red dye No. 3 years ago,” she noted. “Yet big food manufacturers lobbied hard to delay this decision because these artificial dyes are cheap, convenient and profitable.”

Red dye No. 3 is often used in strawberry flavoring, according to experts. (iStock)

The dye was commonly used in products that are primarily marketed to children, she noted, such as colorful lollipops, candies and breakfast cereals.

“Our kids deserved better, and it’s frustrating that it took this long for action to be taken,” Muhlstein added.

‘Stay informed’

Muhlstein commented that while the ban is a “step forward,” it’s also a reminder to “stay informed about what we’re feeding our families.”

Red dye No. 3 is included in other products that aren’t so obvious, including some pre-packaged vegan meats, fruit cups, mini muffin snacks, mashed potatoes, yellow rice and sugar-free water flavors, according to experts.

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DeCicco encouraged consumers to always read the ingredient label and to look for natural replacements for these products.

The dye was commonly used in products that are primarily marketed to children, such as colorful lollipops, candies and breakfast cereals. (iStock)

“It’s not about deprivation or restriction – I always say it’s about eating foods with high-quality ingredients,” she said. “The ingredients matter more than anything else, and they’re out there.”

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“I have worked with many families with kids who have ADHD, and removing sugar and artificial food dyes and additives can in some cases lessen symptoms (as one part of treatment),” DeCicco added.

Colorful food without carcinogens

While nutritionists recommend that consumers stay away from foods that contain red dye or erythrosine on the label, there are healthier, natural alternatives to keep food fun.

Using alternatives for red dye like pomegranate juice or fruit powder can keep food fun, according to nutritionists. (iStock)

Muhlstein recommends adding 1 to 2 tablespoons of pomegranate juice to a baking recipe, such as vanilla cake, to give the batter a natural red hue.

She also suggests mixing crushed-up, freeze-dried strawberries into white frosting or whipped cream.

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“Beetroot powder, hibiscus powder and even mashed raspberries are great alternatives, too,” she added.

Fox News Digital’s Melissa Rudy contributed to this report.

The Avian Influenza has claimed the lives of a Harbor Seal and a Chilean Flamingo at Chicago’s Lincoln Park Zoo.

The zoo announced they received results that confirmed the highly pathogenic Avian Influenza was the cause of Teal, a Chilean Flamingo, and Slater, a Harbor Seal’s death.

“This is sad news for wildlife and for the zoo team. Not only are we facing the first known cases of HPAI in animals in our care, but we’ve lost two amazing animals,” said Director of Veterinary Services Lester E. Fisher and Dr. Kathryn Gamble in a statement. “While highly pathogenic avian influenza is a naturally occurring virus in free-ranging waterfowl, more mammal species have been reported to be susceptible to HPAI since 2022.”

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The zoo was unable to confirm the source of the exposure, but the Centers for Disease Control say that HPAI is spread through saliva, nasal secretion and the feces of infected birds.

They did say that zoo visitors are not at risk of contracting the disease from the animals at Lincoln Park zoo.

“Because highly pathogenic avian influenza is spread by free-ranging birds, it is no riskier to visit Lincoln Park Zoo than to enjoy a walk outdoors,” said President & CEO and ornithologist Megan Ross. “The zoo remains a safe place to connect with the animals in our care.”

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The zoo announced they received results that confirmed the highly pathogenic Avian Influenza was the cause of Teal, a Chilean Flamingo and Slater, a Harbor Seal’s death. (Lincoln Park Zoo)

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The zoo has been monitoring HPAI, so there is a response plan in place. The plan addresses staff and animals. It includes personal protective equipment and removing cross contamination between species while monitoring individual animal behavior, according to a statement by the zoo. They have also closed the McCormick Bird House and will be closed until further notice.

The zoo announced they received results that confirmed the highly pathogenic Avian Influenza was the cause of Teal, a Chilean Flamingo and Slater, a Harbor Seal’s death. (Lincoln Park Zoo)

The zoo also said in their statement that it’s important to keep personal pets indoors and away from wildlife.

“Sharing this news of highly pathogenic avian influenza in the area is important for our community at large,” said Director of the Urban Wildlife Institute Seth Magle. “To protect yourself, do not handle wildlife. Additionally, keep your pets safe by keeping cats indoors and dogs on a leash away from wildlife.”